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Nuvalent

Biotechnology

Cambridge, Massachusetts, United States
200-500 employees
Founded 2017

Nuvalent is a clinical-stage biopharmaceutical company developing precisely targeted kinase-inhibitor therapies for patients with cancer, with parallel lead programs in ROS1-positive and ALK-positive non-small cell lung cancer (NSCLC). Using structure-based drug design, it develops small molecules designed to overcome kinase resistance and improve target selectivity.

  • Zidesamtinib (ROS1 inhibitor for ROS1-positive NSCLC)
  • Neladalkib (ALK inhibitor for ALK-positive NSCLC; NDA accepted with FDA Priority Review, PDUFA date November 27, 2026)
  • Pipeline of multiple discovery-stage research programs

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